Tuesday, April 27, 2010

Singulair [Montelukast Sodium] - Anti-Allergic Medicine


Singulair [Montelukast Sodium] is an anti-allergic drug which is used for the treatment of asthma and seasonal allergic rhinitis also known as hay fever. It contains Montelukast Sodium which is an oral leukotriene receptor antagonist. Leukotrienes are naturally occurring chemicals group in the body which promotes inflammation in case of asthma seasonal allergic rhinitis and other allergic diseases. When leukotrienes are released they bind on other cells and stimulate them to promote inflammation. Montelukast prevents some leukotrienes from binding them which helps to minimize breathing problem sneezing runny and itchy nose caused by asthma and allergies. Singulair does not affect the elimination of other drugs because montelukast does not inhibit enzymes CYP2C9 or CYP3A4 present in the liver that are important in breaking down and eliminating many drugs. Singulair is safe and effective even for a 6 months old baby. The oral granule pack of the allergy medicine Singulair contains inactive ingredients like mannitol hydroxypropyl cellulose and magnesium stearate. Chewable anti-allergic tablets contain inactive ingredients like mannitol microcrystalline cellulose hydroxypropyl cellulose red ferric oxide croscarmellose sodium cherry flavor aspartame and magnesium stearate. This allergy medicine contain inactive ingredients like microcrystalline cellulose lactose monohydrate croscarmellose sodium hydroxypropyl cellulose and magnesium stearate. Film coating of tablets contain hydroxypropyl methylcellulose hydroxypropyl cellulose titanium dioxide red ferric oxide yellow ferric oxide and carnauba wax. Singulair [Montelukast Sodium] is approved by FDA in 1998.

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